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21_Symptoms and Signs_Occ Environ 2025_Cowl_NOANSW ...
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This comprehensive review addresses the approach to pulmonary symptoms, primarily cough, dyspnea, and hemoptysis, and explores occupational and environmental lung diseases relevant for pulmonary medicine board exams.<br /><br />Cough evaluation distinguishes acute (<3 weeks) and chronic (>8 weeks) causes. Acute cough is most often viral and self-limited; treatment is generally supportive. Chronic cough requires a systematic approach, considering upper airway cough syndrome (UACS), asthma variants including cough-variant asthma and non-asthmatic eosinophilic bronchitis, GERD, ACE inhibitor-induced cough, and cough hypersensitivity syndrome. Empiric therapies, targeted testing (e.g., methacholine challenge, imaging), and detailed history are key. Hemoptysis workup requires confirming bleeding source, assessing severity, and identifying causes—most commonly infections or malignancy—with bronchoscopy and imaging guided by clinical status.<br /><br />Dyspnea evaluation incorporates clinical scoring systems like the Borg and Medical Research Council scales and differential diagnosis spanning cardiac, pulmonary, gastrointestinal, and psychological etiologies.<br /><br />A significant portion focuses on occupational lung diseases (pneumoconioses) caused by inhalation of mineral dusts: silicosis, coal worker’s pneumoconiosis, asbestosis, and related pleural disease. Silicosis is the most prevalent occupational lung disease globally, associated with increased lung cancer risk and characterized radiographically by egg-shell calcifications and progressive massive fibrosis (PMF). Coal worker’s pneumoconiosis shares features but is not linked to cancer, while asbestos exposure leads to pleural plaques, benign effusions, and malignancies like mesothelioma.<br /><br />Other occupational diseases include hypersensitivity pneumonitis (HP), metal fume fever, byssinosis (cotton exposure-related airway disease), and ornithosis (bird-borne infection). Work-related asthma is classified into immunologic-induced (high vs. low molecular weight agents) and irritant-induced asthma (RADS).<br /><br />Toxic inhalations highlight the importance of particle properties (solubility, density, exposure duration) with examples including ammonia, nitrogen oxides (silo-filler’s disease), sulfur dioxide, and hydrogen sulfide.<br /><br />Altitude-related illnesses—acute mountain sickness and pulmonary edema—are discussed with prevention and treatment emphasizing gradual ascent, acetazolamide use, and oxygen supplementation.<br /><br />In summary, a methodical history emphasizing occupational/environmental exposures combined with clinical, radiologic, and functional assessments is crucial for diagnosis and management of pulmonary symptoms and diseases. This guide is valuable for board preparation and clinical practice in pulmonary medicine.
Meta Tag
Concept
Cough
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Hemoptysis
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Dyspnea
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Upper Airway Cough Syndrome
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Hemoptysis Evaluation
Keywords
pulmonary symptoms
chronic cough
hemoptysis
dyspnea evaluation
occupational lung disease
silicosis
asbestosis
hypersensitivity pneumonitis
work-related asthma
acute mountain sickness
Cough
Hemoptysis
Dyspnea
Upper Airway Cough Syndrome
Hemoptysis Evaluation
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