Advanced Management Strategies in Severe Asthma and COPD (MC)-Audience Response Questions in COPD MARCINIUK

Audience Response Questions in COPD MARCINIUK

Pdf Summary

The COPD Master Class 2024, presented by Dr. Darcy D. Marciniuk, offers a rapid-fire Q&A format to enhance the understanding of Chronic Obstructive Pulmonary Disease (COPD) management. The session targets various aspects of COPD care, beginning with determining the participant's experience level in treating COPD patients, whether in general practice or specialized care.<br /><br />Key topics include the advantages of LABA/LAMA/ICS (Long-Acting Beta-Agonist/Long-Acting Muscarinic Antagonist/Inhaled Corticosteroid) combinations over LABA/LAMA alone in treating moderate to severe COPD, highlighting improvements in lung function, reduced acute exacerbations (AECOPDs), better quality of life, and potentially reduced mortality. Roflumilast, azithromycin, and N-acetylcysteine are evaluated for their effectiveness in patients with a high risk of exacerbations.<br /><br />Another focus is on the use of maintenance macrolide therapy, which prolongs the time to the next AECOPD, enhances quality of life, and reduces serious adverse events, though considerations about antibiotic resistance and patient selection are important. Dupilumab, a biologic treatment for COPD patients with elevated eosinophil counts, shows promise in reducing exacerbation rates and improving lung function, with effects on biomarkers like FeNO and IgE being explored.<br /><br />The impact of initiating pulmonary rehabilitation (PR) within 90 days post-discharge in older adults hospitalized for COPD is also discussed, showing benefits in reducing re-hospitalizations and lowering mortality. This comprehensive session underscores the necessity of tailored approaches in COPD management, uninhibited by a one-size-fits-all methodology, with an emphasis on up-to-date research and clinical practice for optimal patient outcomes.

Keywords

COPD Master Class 2024

Chronic Obstructive Pulmonary Disease

COPD

LABA/LAMA/ICS combinations

acute exacerbations

roflumilast

maintenance macrolide therapy

dupilumab

pulmonary rehabilitation

eosinophil counts

tailored COPD management

COPD

Chronic Obstructive Pulmonary Disease