CHEST 2023 On Demand Pass-Controversies in Asthma-COPD Overlap: A Pro-Con Debate

Video Transcription

Video Summary

The controversy around the asthma COPD overlap (ACO) centers on whether it is a distinct entity or if it is better understood as a spectrum of one disease. Proponents of ACO argue that it is an entity with a unique set of characteristics and clinical implications. They point to evidence that suggests there is significant overlap between asthma and COPD, with many patients having a history of both conditions. They also highlight the higher symptom burden and comorbidities associated with ACO compared to asthma and COPD alone. They argue that ACO should be recognized and treated as a distinct disease, and that the treatable traits approach can be effective in managing ACO. This approach involves identifying specific traits or features of the disease that are treatable with targeted therapies. Proponents argue that this approach allows for a more personalized and effective treatment of ACO patients. On the other hand, critics of ACO argue that there is insufficient evidence to support its existence as a separate entity. They contend that the traits and characteristics attributed to ACO can also be seen in asthma and COPD alone. They suggest that the current stepped approach to treatment, which involves a systematic progression of therapies based on symptom severity, is sufficient for managing ACO. They caution against overusing the treatable traits approach, which they argue may not be supported by strong evidence or be practical in a clinical setting. In conclusion, the controversies in asthma COPD overlap center on whether it should be recognized as a distinct entity and if the treatable traits approach is the most effective way to manage it. While proponents argue that ACO is a unique disease entity with its own set of characteristics and clinical implications, critics argue that there is insufficient evidence to support this claim and that the stepped approach to treatment is sufficient for managing ACO.

Meta Tag

Category Obstructive Lung Diseases

Session ID 1002

Speaker Peter Gibson

Speaker Nicola Hanania

Speaker Garbo Mak

Speaker Arjun Mohan

Speaker Neveda Murugesan

Track Obstructive Lung Diseases

Track Allergy and Airway

Keywords

asthma COPD overlap

ACO controversy

distinct entity debate

spectrum of one disease

overlap between asthma and COPD

symptom burden in ACO

comorbidities in ACO

treatable traits approach

personalized treatment for ACO

insufficient evidence for ACO existence