CHEST 2023 On Demand Pass-Inflammation and Immunity in Cardiovascular Disease

Video Transcription

Video Summary

In this study, researchers analyzed data from 2,425 participants to explore the relationship between cardiac stress biomarkers and left ventricular hypertrophy (LVH) and to assess the predictive value of these biomarkers for heart failure. The biomarkers of interest were GDF15, ST2, high-sensitivity troponin, and BNP. Participants underwent echocardiographic testing to determine LVH status. The results showed that the levels of cardiac stress biomarkers varied across different types of LVH geometry, with the highest levels observed in concentric hypertrophy. Furthermore, the presence of elevated biomarkers was associated with an increased risk of heart failure, with the combination of LVH and elevated biomarkers conferring an even higher risk. The study suggests that the combination of LVH and certain cardiac stress biomarkers may serve as a predictor of heart failure, and that these biomarkers may have different roles in the various types of LVH remodeling. However, it is important to note that the study was cross-sectional, so causality and temporality could not be fully examined. Further research is needed to validate these findings in larger cohorts and to explore the role of these biomarkers in different populations.

Meta Tag

Category Cardiovascular Disease

Session ID 4033

Speaker Lucas Chen

Speaker Kristin Corey

Speaker Sany Kumar

Speaker Anand Reddy Maligireddy

Speaker Renuka Reddy

Speaker Omar Tamimi

Track Cardiovascular Disease

Keywords

cardiac stress biomarkers

left ventricular hypertrophy

LVH

predictive value

heart failure

GDF15

ST2

high-sensitivity troponin

BNP