CHEST Immersion Severe Asthma May 29-30, 2024-Bronchoprovocation- Mosnaim

Bronchoprovocation- Mosnaim

Pdf Summary

Dr. Giselle Mosnaim, a specialist in Allergy and Immunology, discusses bronchoprovocation tests for diagnosing airway diseases like asthma. These tests are crucial for understanding airway hyperresponsiveness (AHR) which is a key feature of asthma. Direct and indirect challenge tests have varying sensitivities and specificities for diagnosing asthma. AHR is linked to asthma symptoms, decline in lung function, and may guide treatment decisions.<br /><br />Different stimuli are used in these tests, such as methacholine for direct AHR and exercise or allergens for indirect AHR. Interpretation of test results and safety considerations are essential. The document provides clinical cases demonstrating the importance of bronchoprovocation tests in diagnosing or excluding asthma in individuals with respiratory symptoms. For instance, a patient with unexplained cough and exertional dyspnea was found not to have asthma but rather allergic rhinitis and postural orthostatic tachycardia syndrome.<br /><br />Understanding AHR through these tests helps in selecting appropriate therapy and monitoring treatment intensity. Identifying the specific phenotype of asthma through these tests can optimize patient care. The document explains the methodology, safety, and interpretation of different challenge tests used to diagnose asthma accurately, emphasizing the significance of these tests in clinical practice.

Keywords

Dr. Giselle Mosnaim

Allergy and Immunology

bronchoprovocation tests

airway diseases

asthma

airway hyperresponsiveness

AHR

methacholine

exercise

allergens