CHEST Immersion Severe Asthma May 29-30, 2024-FeNO & Oscillometry-Khurana

FeNO & Oscillometry-Khurana

Pdf Summary

Dr. Sandhya Khurana, a professor at the University of Rochester, specializes in asthma and uses Fractional exhaled Nitric Oxide (FeNO) and Oscillometry for diagnosis and treatment selection. FeNO, measured by exhalation at a steady flow rate, is elevated in Type 2 inflammation, aiding in asthma diagnosis and predicting exacerbations. It is affected by various factors like atopy and medication. FeNO also predicts responses to Inhaled Corticosteroids (ICS) and biologics. Oscillometry measures lung mechanics by applying pressure waves during breathing, analyzing impedance, resistance, and reactance. It provides insight into airflow limitation and small airway dysfunction. While advantageous for its ease and detailed analysis of lung mechanics, oscillometry has limitations like poor specificity and technical challenges. In a clinical context, FeNO guided the diagnosis and treatment of asthma in patients like Sarah, John, and Emily, showing improvement in symptoms with appropriate interventions. FeNO and oscillometry continue to play evolving roles in asthma management by providing valuable information for personalized care. However, it is crucial to interpret these measurements alongside clinical factors rather than standalone tools.

Keywords

Dr. Sandhya Khurana

University of Rochester

Asthma

Fractional exhaled Nitric Oxide

FeNO

Oscillometry

Type 2 inflammation

Inhaled Corticosteroids

Biologics

Lung mechanics