CHEST Pulmonary Arterial Hypertension Immersion Program October 25, 2023-Guidelines and Consensus-Rajagopal

Guidelines and Consensus-Rajagopal

Pdf Summary

This document provides an overview of the guidelines and consensus proceedings on the treatment of Pulmonary Hypertension (PH). It distinguishes between consensus proceedings and guidelines, highlighting that guidelines require a systematic review of the literature and a rigorous assessment of the evidence quality. <br /><br />The document also describes the structure of guidelines, which cover various aspects of PH including definitions and classifications, diagnostic algorithms, screening recommendations, workup protocols, risk assessment tools, treatment algorithms, and follow-up strategies. It mentions that the guidelines provide information on the diagnostic classification of PH, which includes different subtypes and the conditions associated with PH.<br /><br />The guidelines also emphasize the importance of risk stratification in determining the severity of PH. It discusses the various risk assessment tools that can be used to evaluate the condition and guide treatment decisions.<br /><br />Furthermore, the document mentions the different treatments available for PH, including specific drugs and strategies. It highlights the historical timeline of PH treatment, from the development of synthetic PGI2 in the 1980s to the recent approval of new drugs such as treprostinil DPI.<br /><br />The document also acknowledges the differences between clinical trial evidence and real-world use of PH therapies. It mentions that while clinical trials provide valuable data on the efficacy and safety of treatments, real-world experience and expert interpretation in guidelines help inform clinical practice and consider practical metrics such as quality of life and disability.<br /><br />Overall, the document underscores the importance of guidelines and consensus proceedings in guiding the diagnosis, treatment, and management of PH, providing a comprehensive overview of the available evidence and expert recommendations in the field.

Keywords

Pulmonary Hypertension

Guidelines

Consensus proceedings

Risk assessment tools

Treatment algorithms

Diagnostic classification

Subtypes

Pharmacological treatments

Clinical trial evidence

Quality of life