Cystic Fibrosis Spotlight-Cystic Fibrosis in the ICU

Video Transcription

Video Summary

In this video transcript, the speakers discuss the non-pulmonary complications and management of patients with cystic fibrosis (CF) in the ICU. They cover a range of topics including acute pancreatitis, cholecystitis, liver disease, diabetes complications, distal intestinal obstruction syndrome (DIOS), nephrolithiasis, anaphylaxis, and acute kidney injury (AKI). Each complication is discussed in terms of its prevalence in CF patients and its management in the ICU. The speakers emphasize the importance of individualized care and tailoring management strategies to the specific needs of each patient. They also highlight the role of CFTR modulator therapies in improving lung function and reducing morbidity and mortality in CF patients. However, they note that these therapies do not necessarily address the non-pulmonary manifestations of CF, and that clinicians should be prepared to manage these complications in the ICU. The speakers provide practical tips and recommendations for managing these complications, including the use of tranexamic acid for hemoptysis, avoidance of bronchoscopy in cases of massive hemoptysis, and the use of pancreatic enzyme replacement therapy in patients on enteral feedings. They also discuss the importance of multidisciplinary care and collaboration with pharmacists to ensure optimal patient outcomes. Overall, the speakers stress the importance of understanding and managing the non-pulmonary complications of CF in the ICU to provide comprehensive and individualized care for patients with this complex disease.

Meta Tag

Category Genetic and Developmental Disorders

Speaker Sunjay Devarajan, MD

Speaker Gretchen Winter, MD

Speaker Elliot Dasenbrook

Speaker Meilinh Thi, DO

Keywords

non-pulmonary complications

management

cystic fibrosis

ICU

acute pancreatitis

cholecystitis

liver disease

diabetes complications

distal intestinal obstruction syndrome

CFTR modulator therapies

CF