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Pulmonary Embolism Management: Unraveling Controve ...
Post Pulmonary Embolism Dyspnea pp
Post Pulmonary Embolism Dyspnea pp
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Pdf Summary
The document is a comprehensive medical presentation on post-pulmonary embolism (PE) dyspnea, including case analysis, evaluation, diagnosis, and management of the condition. It focuses on a case study of a 47-year-old woman with a history of obesity and anxiety, among other health issues, who suffered from an intermediate-high-risk PE. Despite initial treatment with EKOS and DOAC, she experienced severe dyspnea, affecting her daily functioning.<br /> <br />The patient's workup revealed persistent filling defects in her lungs and impaired cardiac parameters, indicating potential Chronic Thromboembolic Pulmonary Hypertension (CTEPH) or Chronic Thromboembolic Disease (CTED). Various evaluations, such as a Six-Minute Walk Test, Pulmonary Function Test, and V/Q scan, were conducted to assess her condition. A highlight of the evaluation was Cardiopulmonary Exercise Testing (CPET), which showed high ventilatory deadspace and inadequate stroke volume augmentation during exercise, suggesting persistent pulmonary artery obstruction.<br /><br />The management of CTEPH involves referral to specialized centers for surgical intervention, such as pulmonary endarterectomy, which was performed on the patient, significantly improving her functional status. Other treatment options discussed include Balloon Pulmonary Angioplasty for inoperable cases and medical therapies using drugs like Riociguat and Treprostinil for residual pulmonary hypertension.<br /><br />The document highlights the significance of evaluating exercise intolerance and dyspnea after an acute PE, with emphasis on differentiated phenotypes of post-PE syndrome and management strategies for identified diseases. Ultimately, it emphasizes the need for specialized intervention in treating such complex conditions, with a focus on advanced therapies and precise patient evaluation.
Keywords
post-pulmonary embolism dyspnea
case study
Chronic Thromboembolic Pulmonary Hypertension
Cardiopulmonary Exercise Testing
pulmonary endarterectomy
Balloon Pulmonary Angioplasty
Riociguat
Treprostinil
exercise intolerance
post-PE syndrome
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