Pulmonary Literature Review and Complex Case Presentations Post Graduate Course-Update on Pulmonary Hypertension and Thromboembolic Disease Stieger

Update on Pulmonary Hypertension and Thromboembolic Disease Stieger

Pdf Summary

The document outlines a comprehensive session on pulmonary hypertension and thromboembolic diseases, presented by Dr. David J Steiger. The session is accessible through a QR code or online platform. Key areas covered include anticoagulation management for thromboembolic disease in cancer patients, catheter-directed interventions in pulmonary embolism (PE), and the evolution of therapeutics for pulmonary hypertension.<br /><br />The session's lesson objectives delve into the anticoagulation strategies for cancer-related venous thromboembolism (VTE), the efficacy of catheter-directed thrombectomy versus embolectomy, and the significance of social determinants in managing PE. Among recent studies, the CANVAS trial assessed different anticoagulants for VTE in cancer patients, revealing similar efficacy between direct oral anticoagulants (DOACs) and Low Molecular Weight Heparin (LMWH), despite the varying bleeding risks associated with each.<br /><br />Pulmonary hypertension management updates include emerging treatments like Sotatercept, a novel agent in treating Group 1 Pulmonary Artery Hypertension. The session also discusses mechanical thrombectomy, highlighted by the FLOWTriever System's safety and efficacy in treating intermediate and high-risk PE, with results indicating rapid hemodynamic improvements and reduced ICU utilization.<br /><br />Social determinants of health reveal racial and economic disparities affecting PE management and mortality outcomes. Such factors underscore the need for equitable healthcare access, which could improve mortality rates and access to advanced therapies.<br /><br />The session concludes with an exploration of Group 3 Pulmonary Hypertension management, particularly in relation to lung disease, noting the limited evidence supporting the use of PAH-approved drugs in COPD treatment.<br /><br />This summary provides an overview of the session's key topics and findings, emphasizing the advancements and challenges in managing complex pulmonary conditions.

Keywords

pulmonary hypertension

thromboembolic diseases

anticoagulation management

cancer patients

catheter-directed interventions

social determinants

Sotatercept

FLOWTriever System

racial disparities

Group 3 Pulmonary Hypertension

Pulmonary Hypertension