TEST - Book of PDFs-01_Bourjeily Chronic lung disease and gynecologic and obstetric

01_Bourjeily Chronic lung disease and gynecologic and obstetric_CMS.pptx

Pdf Summary

This document discusses the impact of cystic fibrosis (CF) on fertility in female patients and the risks of mortality in pulmonary hypertension. In CF, up to 98% of men are infertile, while fertility in females with CF is less clear but still relevant with increasing numbers of pregnancies associated with CF. CF affects the reproductive system by causing abnormalities in the cervix, uterus, menarche, and the hypothalamic pituitary axis. The ability to conceive in CF patients is impacted due to lack of cyclical changes in cervical mucus and altered bicarbonate secretion in the uterus. However, around 50% of women with CF are still able to conceive. <br /><br />In the case of a 25-year-old woman with CF seeking preconception counseling, it is important to explain the impact of CF on her ability to conceive. The correct answer is that if she has regular menses, her chances to conceive are extremely high. In another case of a 30-year-old woman with idiopathic pulmonary hypertension (PH) seeking contraception and pregnancy advice, it is important to emphasize the importance of contraception and inform her about the significant risk of death with pregnancy. The use of hormonal contraception is contraindicated in PH, and barrier methods should be offered. <br /><br />Furthermore, the document provides information on contraceptive methods and their efficacy in patients with PH. It also discusses the safety of various drugs used to treat PH during pregnancy and lactation. Overall, the document highlights the importance of preconception counseling, contraception, and understanding the risks associated with CF and PH in relation to fertility and pregnancy.

Keywords

cystic fibrosis

fertility

female patients

mortality

pulmonary hypertension

reproductive system

conception

preconception counseling

contraception

pregnancy advice